Tissue Damage Markers after a Spinal Manipulation in Healthy Subjects: A Preliminary Report of a Randomized Controlled Trial

Table 2

Blood concentrations for all groups at each follow-up period. Statistical significance and effect size for group-by-time interaction.

		Pre-T	Post-0 H	Post 2 H	value	Eta^2
		Mean ± SD	Mean ± SD	Mean ± SD
CPK (U/L)	Control	74.90 ± 17.21	74.10 ± 17.12	74.40 ± 16.57	0.425	0.065
	Thoracic	72.00 ± 13.73	72.10 ± 16.00	71.10 ± 19.09
	Cervical	65.10 ± 14.78	65.20 ± 16.29	68.10 ± 16.38
LDH (U/L)	Control	276.03 ± 57.30	283.43 ± 44.29	268.11 ± 47.02	0.167	0.112
	Thoracic	297.20 ± 52.66	294.70 ± 52.69	289.80 ± 67.36
	Cervical	275.90 ± 43.40	276.00 ± 28.20	302.80 ± 82.64
Enolase (ng/mL)	Control	9.48 ± 1.81	8.90 ± 1.24	8.86 ± 1.29	0.235	0.100
	Thoracic	9.09 ± 1.50	9.52 ± 1.41	9.42 ± 2.95
	Cervical	9.57 ± 3.26	9.23 ± 1.97	11.57 ± 6.17
CPR (mg/L)	Control	1.41 ± 1.00	1.61 ± 1.02	1.53 ± 1.19	0.486	0.058
	Thoracic	0.56 ± 0.30	0.50 ± 0.27	0.50 ± 0.30
	Cervical	1.48 ± 1.16	1.48 ± 1.22	1.47 ± 1.15
Aldolase (U/L)	Control	3.09 ± 1.60	3.36 ± 1.37	3.50 ± 1.57	0.859	0.019
	Thoracic	3.10 ± 1.06	3.23 ± 1.25	3.17 ± 1.37
	Cervical	3.13 ± 1.02	3.29 ± 0.90	3.63 ± 1.38
Myoglobin (ng/mL)	Control	50.76 ± 31.39	52.18 ± 23.63	70.20 ± 43.56	0.312	0.083
	Thoracic	36.80 ± 10.81	38.30 ± 10.80	36.60 ± 10.60
	Cervical	35.40 ± 20.87	35.80 ± 19.62	39.10 ± 22.19

Pre-T: pretreatment values; Post-0 H: values 0 H after intervention; Post-2 H: values 2 H after intervention; CPK: creatine phosphokinase; LDH: lactate dehydrogenase; CRP: C-reactive protein.