Research Article

Red Cell Distribution Width Is Associated with Presence, Stage, and Grade in Patients with Renal Cell Carcinoma

Table 1

Description and comparison of clinical and laboratory characteristics of the study subjects.

Variables RCC
()
Controls
()
value

Age (years)0.122
Gender (male/female)210/108146/920.284
BMI ( (%))0.370
 <25152 (47.80)124 (52.10)
 ≥25166 (52.20)114 (47.90)
Hypertension ( (%))120 (37.74)86 (36.13)0.723
Diabetes mellitus ( (%))46 (14.47)23 (9.66)0.093
Smoking ( (%))63 (19.81)29 (12.18)0.021
RDW (%)<0.001
HB (g/L)0.001
MCV (fL)0.013
Platelet (109/L)0.001
WBC (109/L)<0.001
Albumin (g/L)<0.001
ESR (mm/h)11.00 (5.00–19.00)6.00 (3.00–10.00)<0.001
Side ( (%))
 Left-sided 135 (42.45)131 (55.04)
 Right-sided 176 (55.35)96 (40.34)
 Two-sided7 (2.20)11 (4.62)
Pathologic type ( (%))
 Clear cell carcinoma 282 (88.68)
 Papillary renal cell carcinoma15 (4.72)
 Chromophobe renal cell carcinoma11 (3. 46)
 Others10 (3.14)
Stage at diagnosis ( (%))
 T1 239 (75.16)
 T2 28 (8.81)
 T3 45 (14.15)
 T4 6 (1.89)
 M1 20 (6.29)
 M0 298 (93.71)
Fuhrman grading of clear cell carcinoma ( (%))
 Grade I 22 (7.80)
 Grades I-II 35 (12.41)
 Grade II 129 (45.74)
 Grades II-III 41 (14.54)
 Grade III 47 (16.67)
 Grades III-IV 7 (2.48)
 Grade IV 1 (0.35)

Data are expressed as (%), median (IQR), or mean ± SD. BMI: body mass index; RDW: red cell distribution width; HB: hemoglobin; MCV: mean cell volume; WBC: white blood cell; ESR: erythrocyte sedimentation rate.