Haptoglobin 2-2 Genotype Is Associated with TNF-α and IL-6 Levels in Subjects with Obesity
Table 3
Characteristics of the HP 2/HP 2 genotype according to sex. .
HP
2/HP 2
P
Women
Men
Age, years
0.229
Body mass index, kg/m2
0.992
Waist circumference, cm
<0.001
Total body fat, %
<0.001
Systolic blood pressure, mmHg
0.008
Diastolic blood pressure, mmHg
0.172
Fasting glucose, mg/dL
0.148
Total cholesterol, mg/dL
0.778
HDL-cholesterol, mg/dL
0.498
LDL-cholesterol, mg/dL
0.146
Triglycerides, mg/dL*
128 (100–168)
192 (143–252)
<0.001
TNF-α, pg/mL*
156.5 (90.1–301.8)
216.4 (99.9–314.8)
0.502
IL-6, pg/mL*
4.3 (1.0–8.7)
4.8 (1.0–10.8)
0.983
hsCRP, mg/L*
4.2 (2.7–8.9)
2.2 (1.0–8.5)
0.007
Values are mean ± standard deviation. hsCRP: high-sensitivity C-reactive protein.
*Median (25–75th percentile), P value estimated using Mann-Whitney U test.