Research Article

Antineutrophil Cytoplasmic Antibody Frequency in Chronic Hepatitis B Patients

Table 2

Comparison of the two groups by P-ANCA, C-ANCA, MPO-ANCA, and PR3-ANCA.

Control ( , %)CHB ( , %)

P-ANCA
 Negative80 (92%)78 (89.7%)
 Positive6 (6.9%)3 (3.4%)0.4
 Borderline positive1 (1.1%)6 (6.9%)0.1
 All positive (any positivity)7 (8%)9 (10.3%)0.6
C-ANCA
 Negative78 (89.7%)71 (81.6%)
 Positive7 (8%)5 (5.7%)0.5
 Borderline positive2 (2.3%)11 (12.6%)0.009
 All positive (any positivity)9 (10.3%)16 (18.4%)0.1
MPO-ANCA
 Negative78 (89.7%)80 (92%)
 Positive5 (5.7%)2 (2.3%)0.4
 Borderline positive4 (4.6%)5 (5.7%)1
 All positive (any positivity)9 (10.3%)7 (8%)0.6
PR3-ANCA
 Negative81 (93.1%)68 (78.2%)
 Positive1 (1.1%)7 (8%)0.06
 Borderline positive5 (5.7%)12 (13.8%) 0.07
 All positive (any positivity)6 (6.9%)19 (21.8%)0.005

CHB: chronic hepatitis B; ANCA: antineutrophil cytoplasmic antibody; P: perinuclear; C: cytoplasmic; MPO: myeloperoxidase; and PR3: proteinase 3.