Serum Creatinine Level: A Supplemental Index to Distinguish Duchenne Muscular Dystrophy from Becker Muscular Dystrophy

Table 2

Serum creatinine levels in DMD and BMD patients (age 2–12 yr).

Age (y)	DMD			BMD				P
	Patients ()	Mean ± SD/M (P25–P75) (μmol/L)	Original value (μmol/L)	Patients ()	Mean ± SD/M (P25–P75) (μmol/L)	Original value (μmol/L)
2	5	15.80 ± 3.962		1		23	N.A.
3	10	14.95 ± 2.114		2		14; 24	N.A.
4	13	17.46 ± 4.875		5	26.00 ± 2.236		−2.670	0.008^*
5	10	15.20 ± 2.530		5	23.60 ± 4.393		−3.009	0.003^*
6	13	16.69 ± 4.461		2		28; 37	N.A.
7	16	15.19 ± 2.762		5	25 (24.50–26.50)		−3.321	0.001^*
8	32	15 (12.25–19.75)		1		21	N.A.
9	15	14.47 ± 3.623		4	25.25 ± 8.098		−2.824	0.005^*
10	4	19.75 ± 4.031		0	N.A.	N.A.	N.A.
11	7	15.14 ± 3.532		2		32; 41	N.A.
12	3		16; 16; 19	2		18; 31	N.A.

DMD: Duchenne muscular dystrophy; BMD: Becker muscular dystrophy; SD; standard deviation; N.A.: not available.
Serum creatinine values are reported as mean ± SD (normal distribution) or as median and the 25th and 75th percentiles (M (P₂₅–P₇₅)). When , the original serum creatinine value is presented.
^*P values < 0.0125 are considered statistically significant for multiple comparison by using Bonferroni test.