(a) Characteristics (%) Quartiles of 25(OH)D valueQ1 Q2 Q3 Q4 25(OH)D (nmol/L) 28.8 ± 5.6 43.2 ± 3.9 55.6 ± 3.4 76.1 ± 12.3 <0.001 25(OH)D (ng/mL) 11.5 ± 2.2 17.3 ± 1.6 22.2 ± 1.4 30.4 ± 4.9 <0.001 Age, years 75.5 ± 14.3 75.8 ± 12.9 75.0 ± 12.1 70.9 ± 12.8 0.058 Smoking status, (%) 0.384 Current smoker, (%) 18 (21.7) 14 (16.7) 10 (11.9) 17 (20.2) Past smoker, (%) 13 (15.7) 21 (25.0) 17 (20.2) 21 (25.0) Never smoked, (%) 52 (62.7) 49 (58.3) 57 (67.9) 46 (54.8) Angina pectoris, (%) 44 (53.0) 45 (53.6) 39 (46.3) 39 (46.4) 0.663 CHF, (%) Killip class 2–4 43 (51.8) 26 (31.0) 20 (23.8) 17 (20.2) <0.001 History of previous MI, (%) 30 (36.1) 25 (29.8) 25 (29.8) 22 (26.2) 0.567 CABG, (%) 6 (7.2) 3 (3.6) 8 (9.5) 3 (3.6) 0.279 PCI, (%) 1 (1.2) 2 (2.4) 7 (8.3) 8 (9.5) 0.035 Hypertension, (%) 41 (49.4) 39 (46.4) 40 (47.6) 37 (44.4) 0.917 History of DM 1, (%) 1 (1.2) 1 (1.2) 0 (0.0) 1 (1.2) 0.798 History of DM 2, (%) 11 (13.3) 12 (14.3) 13 (15.5) 9 (10.7) 0.828 STEMI, (%) 11 (13.3) 7 (8.3) 3 (3.6) 7 (8.3) 0.164 TnT release, (%) 46 (55.4) 40 (47.6) 42 (50.0) 34 (40.5) 0.277 eGFR (μ mol L−1 ) 52.3 ± 18.4 54.9 ± 17.4 53.9 ± 17.8 58.9 ± 15.1 0.079 Cholesterol/statin, (%) 43 (51.8) 46 (54.8) 45 (53.6) 45 (53.6) 0.985 Beta-blocker, (%) 33 (39.8) 32 (38.1) 38 (45.2) 23 (27.4) 0.112 Known CHD, (%) 59 (71.1) 56 (66.7) 56 (66.7) 50 (59.5) 0.465 BMI (kg/m2 ) 25.4 ± 4.8 25.5 ± 4.6 25.2 ± 5.2 24.9 ± 4.0 0.886 BNP quartiles 0.094 Q1 17 (20.7) 20 (25.0) 17 (21.5) 27 (33.8) Q2 19 (23.2) 23 (28.8) 20 (25.3) 19 (23.8) Q3 15 (18.3) 21 (26.3) 23 (29.1) 21 (26.3) Q4 31 (37.8) 16 (20.0) 19 (24.1) 13 (16.3) hsCRP quartiles 0.995 Q1 20 (24.1) 19 (22.6) 21 (25.0) 24 (28.6) Q2 21 (25.3) 20 (23.8) 22 (26.2) 20 (23.8) Q3 21 (25.3) 22 (26.2) 19 (22.6) 22 (26.2) Q4 21 (25.3) 23 (27.4) 22 (26.2) 18 (21.4)
Mean ± SD. SD, standard deviation; 25(OH)D, 25-hydroxyvitamin D; CHF, congestive heart failure; MI, myocardial infarction; CABG, coronary artery bypass grafting; PCI, percutaneous coronary intervention; DM, diabetes mellitus; STEMI, ST-elevation myocardial infarction; TnT, troponin T; eGFR, estimated glomerular filtration rate; CHD, coronary heart disease; BMI, body mass index; BNP, B-type natriuretic peptide; hsCRP, high sensitivity C-reactive protein.(b) Characteristics (%) Quartiles of 25(OH)D valueQ1 Q2 Q3 Q4 25(OH)D (nmol/L) 31.7 ± 6.0 46.3 ± 3.0 57.4 ± 3.8 79.9 ± 13.7 <0.001 25(OH)D (ng/mL) 12.7 ± 2.4 18.5 ± 1.2 23.0 ± 1.5 32.0 ± 5.5 <0.001 Age, years 63.6 ± 15.3 66.0 ± 16.3 67.8 ± 12.9 68.6 ± 12.3 0.024 Smoking status, (%) 0.211 Current smoker, (%) 53 (40.5) 44 (33.6) 37 (28.0) 34 (26.0) Past smoker, (%) 53 (40.5) 58 (44.3) 67 (50.8) 63 (48.1) Never smoked, (%) 25 (19.1) 29 (22.1) 28 (21.2) 34 (26.0) Angina pectoris, (%) 46 (35.1) 48 (36.6) 60 (45.5) 54 (41.2) 0.306 CHF, (%) Killip Class 2–4 42 (32.1) 21 (16.0) 32 (24.2) 31 (23.7) 0.026 History of previous MI, (%) 50 (38.2) 46 (35.1) 45 (34.1) 44 (33.6) 0.867 CABG, (%) 18 (13.7) 14 (10.7) 16 (12.1) 19 (14.5) 0.795 PCI, (%) 19 (14.5) 17 (13.0) 18 (13.6) 15 (11.5) 0.903 Hypertension, (%) 44 (33.6) 45 (34.4) 56 (42.4) 59 (45.0) 0.141 History of DM 1, (%) 1 (0.8) 1 (0.8) 1 (0.8) 2 (1.5) 0.894 History of DM 2, (%) 25 (19.1) 14 (10.7) 19 (14.4) 8 (6.1) 0.013 STEMI, (%) 21 (16.0) 28 (21.4) 28 (21.2) 23 (17.6) 0.610 TnT release, (%) 73 (55.7) 74 (56.5) 76 (57.6) 81 (61.8) 0.754 eGFR (μ mol L−1 ) 70.5 ± 21.7 67.0 ± 21.0 68.1 ± 20.6 65.8 ± 21.7 0.312 Cholesterol/statin, (%) 57 (43.5) 62 (47.3) 65 (49.2) 61 (46.6) 0.826 Beta-blocker, (%) 49 (37.4) 44 (33.6) 44 (33.3) 45 (34.4) 0.894 Known CHD, (%) 80 (61.1) 77 (58.8) 85 (64.4) 79 (60.3) 0.817 BMI (kg/m2 ) 26.1 ± 3.9 26.6 ± 4.9 26.0 ± 3.4 25.0 ± 3.5 0.014 BNP quartiles 0.545 Q1 29 (23.4) 35 (27.3) 27 (21.1) 36 (29.5) Q2 30 (24.2) 30 (23.4) 39 (30.5) 27 (22.1) Q3 30 (24.2) 27 (21.1) 36 (28.1) 31 (25.4) Q4 35 (28.2) 36 (28.1) 26 (20.3) 28 (23.0) hsCRP Quartiles 0.904 Q1 30 (22.9) 33 (25.2) 32 (24.2) 36 (27.5) Q2 28 (21.4) 31 (23.7) 35 (26.5) 36 (27.5) Q3 37 (28.2) 34 (26.0) 35 (26.5) 27 (20.6) Q4 36 (27.5) 33 (25.2) 30 (22.7) 32 (24.4)
Mean ± SD. SD, standard deviation; 25(OH)D, 25-hydroxyvitamin D; CHF, congestive heart failure; MI, myocardial infarction; CABG, coronary artery bypass grafting; PCI, percutaneous coronary intervention; DM, diabetes mellitus; STEMI, ST-elevation myocardial infarction; TnT, troponin T; eGFR, estimated glomerular filtration rate; CHD, coronary heart disease; BMI, body mass index; BNP, B-type natriuretic peptide; hsCRP, high sensitivity C-reactive protein.