Prognostic Utility of Vitamin D in Acute Coronary Syndrome Patients in Coastal Norway
Table 4
The univariate and multivariable HRs (95% CI) for quartiles of 25(OH)D.
2-year follow-up
7-year follow-up
Univariate analysis
Multivariable analysis
Univariate analysis
Multivariable analysis
Total population
Total mortality
0.61 (0.37–1.00) = 0.05
0.79 (0.45–1.40) = 0.40
0.66 (0.48–0.89) = 0.008
0.79 (0.57–1.09) = 0.15
Cardiac death
0.70 (0.37–1.34) = 0.29
0.83 (0.40–1.72) = 0.61
NA
NA
SCD
0.59 (0.14–2.44) = 0.46
1.28 (0.26–6.37) = 0.76
NA
NA
TnT pos. population
Total mortality
0.59 (0.33–1.04) = 0.07
0.82 (0.42–1.61) = 0.56
0.60 (0.41–0.87) = 0.008
0.74 (0.49–1.12) = 0.15
Cardiac death
0.71 (0.36–1.41) = 0.33
1.09 (0.49–2.42) = 0.84
NA
NA
SCD
0.58 (0.14–2.44) = 0.46
1.52 (0.30–7.72) = 0.61
NA
NA
Females
Total mortality
0.43 (0.19–0.94) = 0.035
0.65 (0.26–1.62) = 0.36
0.51 (0.32–0.83) = 0.006
0.64 (0.38–1.10) = 0.09
Cardiac death
0.35 (0.13–0.98) = 0.046
0.61 (0.19–2.00) = 0.41
NA
NA
SCD
0.0 (0.00-0.00) = 0.96
NA
NA
NA
Males
Total mortality
0.85 (0.46–1.57) = 0.61
0.81 (0.40–1.65) = 0.56
0.82 (0.56–1.24) = 0.36
0.73 (0.47–1.12) = 0.15
Cardiac death
1.09 (0.46–2.56) = 0.85
0.89 (0.32–2.46) = 0.83
NA
NA
SCD
0.99 (0.20–4.88) = 0.99
1.92 (0.31–12.1) = 0.49
NA
NA
SCD, sudden cardiac death. Adjusted for gender, age, smoking, hypertension, index diagnosis, diabetes mellitus, CHF (defined by Killip-Kimball class at admission; patients in classes 2 to 4 were classified as CHF patients and those in class 1 as non-CHF), history of previous CHD (i.e., history of either angina pectoris, myocardial infarction, percutaneous coronary intervention, or coronary artery bypass graft), hypercholesterolemia/use of statins, TnT >0.01 ng/mL, eGFR, hsCRP, BNP, body mass index (kg/m2), and beta-blockers prior to enrolment.