Postoperative CA19-9 Change Is a Useful Predictor of Intrahepatic Cholangiocarcinoma Survival following Liver Resection

Table 1

Comparison of clinicopathological factors according to preopCA19-9^† in ICC^‡ patients (preopCA19-9 >37 U/mL versus preopCA19-9 ≤37 U/mL).

Factors	PreopCA19-9; ≤37 U/mL; ()	PreopCA19-9; >37 U/mL; ()	value
Age (>65/≤65 years)	18/11	22/23	0.527
Sex (male/female)	19/10	25/20	0.359
Viral hepatitis B (yes/no)	10/19	5/40	0.017
Tumor size (>5/≤5 cm)	17/12	31/14	0.07
Major vascular invasion (yes/no)	3/26	8/37	0.169
Microvascular invasion (yes/no)	9/20	20/25	0.182
Perineural invasion (yes/no)	10/19	17/28	0.253
Lymphatic invasion (yes/no)	10/19	22/23	0.107
Intrahepatic metastasis (yes/no)	8/21	14/31	0.387
T stage, AJCC 6th (I, II/III, IV)	21/8	23/22	0.069
Lymph node metastasis (yes/no)	5/24	15/30	0.104
Resection margin (>1/≤1 cm)	24/5	29/16	0.093
Adjuvant therapy (yes/no)	10/19	13/32	0.399

PreopCA19-9^†: preoperative CA19-9; ICC^‡: intrahepatic cholangiocarcinoma.