Expression of Ribonucleotide Reductase Subunit-2 and Thymidylate Synthase Correlates with Poor Prognosis in Patients with Resected Stages I–III Non-Small Cell Lung Cancer

Figure 1

Representative results of IHC staining of NSCLC tumour specimens for ERCC1, BRCA1, TS, and TUBB3. (a) Negative expression of ERCC1 (final score 0), (b) high expression of ERCC1: nuclear staining (final score 3); (c) negative expression of BRCA1 (final score 0), (d) high expression of BRCA1: cytoplasmic staining (final score 2); (e) negative expression of TS (final score 0), (f) high expression of TS: cytoplasmic staining (final score 1) and nuclear staining (final score 2); and (g) negative expression of TUBB3 (final score 0), (h) high expression of TUBB3: cytoplasmic staining (final score 3).

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