Expression of Ribonucleotide Reductase Subunit-2 and Thymidylate Synthase Correlates with Poor Prognosis in Patients with Resected Stages I–III Non-Small Cell Lung Cancer

<div>Representative results of IHC staining of NSCLC tumour specimens for RRM2, RRM1, and p53R2. (a) Negative expression of RRM2 (final score 0), (b) high expression of RRM2: cytoplasmic staining (final score 3); (c) negative expression of RRM1 (final score 0), (d) high expression of RRM1: cytoplasmic staining (final score 2); and (e) negative expression of p53R2 (final score 0), (f) high expression of p53R2: nuclear staining (final score 3).</div>

Disease Markers

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Figure 2: Expression of Ribonucleotide Reductase Subunit-2 and Thymidylate Synthase Correlates with Poor Prognosis in Patients with Resected Stages I–III Non-Small Cell Lung Cancer 

Figure 2 | Expression of Ribonucleotide Reductase Subunit-2 and Thymidylate Synthase Correlates with Poor Prognosis in Patients with Resected Stages I–III Non-Small Cell Lung Cancer 