Clinicopathological Significance of MicroRNA-20b Expression in Hepatocellular Carcinoma and Regulation of HIF-1α and VEGF Effect on Cell Biological Behaviour

Table 2

Univariate analysis of clinicopathological factors for overall survival.

Variable		Hazard ratio	95% CI	value
Age (years)
≤57	38	1	0.866–1.417	0.350
>57	28	0.728
Gender
Male	57	1	0.912–3.749	0.088
Female	19	1.849
Tumor size (cm)
≥5	42	1	0.264–1.116	0.097
<5	34	0.543
AFP (ng/mL)
≥400	36	1	0.387–1.506	0.436
<400	40	0.434
Metastasis
Yes	47	1	1.396–5.647	0.004
No	29	2.808
Tumor grade
G1	18	1	0.710–2.751	0.333
G2	24	1.398
G3	34
TNM stage
I-II	40	1	1.626–6.946	0.001
III-IV	36	3.360
Tumor recurrence
Yes	46	1	0.171–0.657	0.007
No	30	0.360
Microvascular invasion
Yes	34	1	1.187–5.931	0.017
No	42	2.654
miR-20b
High	45	1	0.129–0.528	0.000
Low	31	0.261

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