Cerebrospinal Fluid Biomarkers in Spinocerebellar Ataxia: A Pilot Study
Table 2
SARA score, Spearman correlation coefficient, and values.
Spearman correlation coefficient ( value):
SARA score and biomarker concentration by disease state
Tau
-Synuclein
DJ-1
GFAP
Control
0.105 (0.895)
0.105 (0.895)
0.105 (0.895)
−0.632 (0.368)
MSA-C
0.900 (0.037)
0.700 (0.188)
0.700 (0.188)
0.400 (0.505)
SCA1
−0.400 (0.505)
−1.00 (0.010)
−0.700 (0.188)
0.300 (0.624)
SCA2
0.058 (0.913)
−0.087 (0.870)
0.319 (0.538)
0.116 (0.827)
SCA6
−0.447 (0.450)
0.224 (0.718)
−0.671 (0.215)
−0.447 (0.450)
Spearman correlations were performed to elucidate any relationship between disease severity (as determined by an increased SARA score) and biomarker concentrations with each disease state. Data are expressed as correlation coefficient ( value). () indicates .