Research Article
The -844 G>A PAI-1 Polymorphism Is Associated with Acute Coronary Syndrome in Mexican Population
Table 1
Demographic and clinical assessments in ACS patients and HS.
| | ACS parameter | Average | ±SD |
| | Ratio male/female | 3.48 | | | Age (years) | 62.91 | ±11.81 | | Glucose (mg/dL) | 164.19 | ±69.47 | | CK (IU/L) | 892.52 | ±1462.96 | | CK-MB (IU/L) | 52.00 | ±163.45 | | Troponin T (ng/mL) | 7.22 | ±14.10 | | Creatinine (mg/dL) | 1.05 | ±0.96 | | Hemoglobin (mg/dL) | 13.62 | ±2.17 |
| | HS parameters | Average | ±SD |
| | Ratio male/female | 1.09 | | | Age (years) | 56.76 | ±8.37 | | Glucose (mg/dL) | 85.53 | ±12.92 | | Triglycerides (mg/dL) | 102.50 | ±24.59 | | HDL (mg/dL) | 49.99 | ±9.99 | | LDL (mg/dL) | 90.30 | ±15.4 |
| | ACS treatment | | (%) |
| | ACE inhibitors | 161 | (54.39) | | Acetylsalicylic acid | 282 | (95.27) | | ARB | 33 | (11.15) | | BB | 151 | (51.01) | | CCB | 36 | (12.16) | | Clopidogrel | 221 | (74.66) | | Heparin | 237 | (80.07) | | Isosorbide | 39 |
(13.18) | | Spironolactone | 101 | (34.12) | | Statins | 242 | (81.76) |
| | ACS Risk factor | | (%) |
| | Obesity | 116 | (39.19) | | DM2 | 143 | (48.31) | | Dyslipidemia | 126 | (42.57) | | HBP | 179 | (60.47) | | Smoking | 170 | (57.43) | | COPD | 8 | (2.70) |
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ACE: angiotensin converting enzyme; ACS: acute coronary syndrome; ARB: angiotensin II receptor blockers; BB: beta blockers; CCB: calcium channel blockers; CK: creatine phosphokinase; CK-MB: creatine phosphokinase MB; COPD: chronic obstructive pulmonary disease; DM2: type 2 diabetes mellitus; HBP: high blood pressure; HS: healthy subjects; SD: standard deviation.
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