Research Article
The -844 G>A PAI-1 Polymorphism Is Associated with Acute Coronary Syndrome in Mexican Population
Table 2
Allele and genotype frequencies of -844 G>A polymorphism in ACS and HS.
| | | HS
(%) | ACS
(%) | OR (CI) | |
| | Allele | | | | | | G | 481 (68.7) | 375 (63.3) | — | — | | A | 219 (31.3) | 217 (36.7) | 1.27 (1.01–1.60) | 0.04 | | Genotype | | | | | | GG | 161 (46.0) | 121 (40.9) | — | — | | GA | 159 (45.4) | 133 (44.9) | 1.11 (0.80–1.55) | 0.52 | | AA | 30 (8.6) | 42 (14.2) | 1.86 (1.10–3.15) | 0.02 | | Dominant model | | | | | | GG | 161 (46.0) | 121 (40.9) | — | — | | GA + AA | 189 (54.0) | 175 (59.1) | 1.23 (0.90–1.69) | 0.19 | | Recessive model | | | | | | GG + GA | 320 (91.4) | 254 (85.8) | — | — | | AA | 30 (8.6) | 42 (14.2) | 1.76 (1.07–2.89) | 0.02 |
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ACS: acute coronary syndrome; CI: confidence interval; HS: healthy subjects; OR: odds ratio. Significant value.
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