Macrophage Migration Inhibitory Factor Promoter Polymorphisms (−794 CATT_5–8 and −173 G>C): Relationship with mRNA Expression and Soluble MIF Levels in Young Obese Subjects

Figure 3

Relative MIF mRNA expression by −173 G>C MIF (rs755622) genotypes in normal-weight and obese subjects. (a) The slightly high MIF mRNA expression was observed in the CC carriers in the total population; (b) the GG carriers had lowest expression in both groups. Relative expression analysis was performed using the method, using GAPDH as the reference gene. Comparison among groups was performed using Mann-Whitney -test; .

(a)

(b)