Site-Specific Secretome Map Evidences VSMC-Related Markers of Coronary Atherosclerosis Grade and Extent in the Hypercholesterolemic Swine

Table 1

Histomorphometric results of RCA and FA segments in 6 CTRL and 6 HF cases.

	CTRL RCA ()	HF FA ()	HF RCA ()	RCA pre-ATH ()	RCA ATH ()
tot. Stary types I–III	0/6	2/6	3/6	3/3	0/3
tot. Stary types IV-V	0/6	0/6	3/6	0/3	3/3
IT (mm)	0.03 ± 0.02	0.06 ± 0.05	0.50 ± 0.44	0.13 ± 0.05	0.86 ± 0.36
IMT ratio (a.u.)	0.11 ± 0.04	0.15 ± 0.05	0.58 ± 0.24	0.32 ± 0.11	0.77 ± 0.07
LA (mm^2)	0.04 ± 0.02	0.06 ± 0.04	2.61 ± 3.42	0.30 ± 0.27	5.00 ± 3.64
LA ratio (a.u.)	0.03 ± 0.02	0.05 ± 0.02	0.97 ± 1.13	0.14 ± 0.10	1.75 ± 1.10

Number of segments () and average value ± SD of maximal IT (IT), maximal intima to media thickness ratio (IMT ratio), lesion area (LA), and lesion to intact wall area ratio of FA and RCA in CTRL and HF cases are reported. RCA segments showing Stary types I–III (RCA pre-ATH) and those displaying Stary types IV-V lesions (RCA ATH) are also grouped separately.