NT-proBNP as Early Marker of Subclinical Late Cardiotoxicity after Doxorubicin Therapy and Mediastinal Irradiation in Childhood Cancer Survivors
Table 2
Right and left ventricular TDI parameters in groups with normal and abnormal NT-proBNP.
Systole ()
Diastole ()
Diastole ()
Abnormal
Normal
Abnormal
Normal
Abnormal
Normal
RVFW a
3.99 ± 0.81
5.03 ± 0.19
<0.001
5.35 ± 1.52
7 ± 0.68
<0.001
2.31 ± 0.7
3.22 ± 0.47
<0.001
RVFW m
6.03 ± 1.7
7.2 ± 0.47
<0.001
8.64 ± 1.88
10.4 ± 0.63
<0.001
4.35 ± 1.41
6.67 ± 0.52
<0.001
RVFW b
7.37 ± 1.62
8.75 ± 0.4
<0.001
10.79 ± 2.2
12.1 ± 0,86
<0.05
5.48 ± 1.1
7.14 ± 0.45
<0.001
LVFW a
3.28 ± 0.5
3.89 ± 0.27
<0.001
5.5 ± 0.95
5.7 ± 0.47
NS
2.31 ± 0.72
3.3 ± 0.32
<0.001
LVFW m
4.27 ± 0.75
<0.001
7.6 ± 1.98
9.7 ± 0.58
<0.001
3.18 ± 0.55
4.2 ± 0.56
<0.001
LVFW b
5.6 ± 1.1
6.5 ± 1.03
<0.05
10.48 ± 2
10.42 ± 0.8
NS
4.72 ± 0.75
5.31 ± 0.79
<0.05
RVFW a, m, b: right ventricular free wall at the apical, middle, and basal parts, respectively. LVFW a, m, b: left ventricular free wall at the apical, middle, and basal parts, respectively. TDI: tissue Doppler imaging.