NT-proBNP as Early Marker of Subclinical Late Cardiotoxicity after Doxorubicin Therapy and Mediastinal Irradiation in Childhood Cancer Survivors

Table 3

Left ventricular diastolic function indices by echocardiography and pulsed TDI and NT-proBNP in exposed and unexposed study groups.

	Unexposed group	Exposed group	value
NT-proBNP (pg/mL)	115 ± 13.7	144.3 ± 28.6	<0.001
Echo parameters
	79 ± 11	82 ± 10	0.219
	8 ± 0.11	5.7 ± 0.8	0.0001
	9.87 ± 1.32	14.38 ± 0.92	0.0001

Systole, : early rapid filling during diastole, : early diastole, and : late diastole.