Research Article
Predictive Performance of a Seven-Plex Antibody Array in Prenatal Screening for Down Syndrome
Table 2
Ratio of MoM-adjusted serum concentrations per analyte for DS compared to controls. Significance is indicated as
;
;
.
| | Total cohort (nDS = 170) | Week 10 (nDS = 43) | Week 11 (nDS = 25) | Week 12 (nDS = 77) |
| PAPP-A (4PL) | | | | | PAPP-A (scaled) | | | | | PAPP-A (AutoDELFIA) | | | | | fβ-hCG (4PL) | | | | | fβ-hCG (scaled) | | | | | fβ-hCG (autoDELFIA) | | 1.25 | | | AFP | 0.90 | 1.01 | 0.85 | | ANGPTL3 | 0.98 | 1.07 | 0.96 | 0.92 | EGF | 1.12 | 1.17 | 1.39 | 0.93 | IGFII | | 1.40 | 1.47 | 1.17 | SOD1 | 1.04 | 1.11 | 1.14 | 0.93 | IgG | 1.13 | 1.32 | 1.04 | 1.04 |
|
|