Research Article

Detection of SNCA and FBN1 Methylation in the Stool as a Biomarker for Colorectal Cancer

Table 3

The positive rate of at least one hypermethylated gene in stool samples.

ā€‰SNCA + FBN1 methylationPositive percent value
PositiveNegative

CRC751484.3%<0.001*
Normal2286.7%

When the markers were used in combination, the test was considered to be positive if one marker reached the threshold and negative if both markers were negative.
Using chi-square for this statistic.
*Statistically significant.