Measurement of Cytokines and Adhesion Molecules in the First 72 Hours after Severe Trauma: Association with Severity and Outcome

Table 3

Relationship between mediators’ levels and degree of inflammatory response (Mann-Whitney test).

		SIRS		SIRS with hypoperfusion		Shock
		Yes	No	Yes	No	Yes	No
IL-10 (admission); pg/mL	Med.			122.5	51.9
	P25–P75			38.4–239	13.2–118
	P			0.01
IL-10 (24 h); pg/mL	Med.	9.19	0.1	13.3	1.16
	P25–P75	0.1–23	0.1–2.45	4.34–25.6	0.1–10.3
	P	0.007		0.002
ICAM-1 (admission); ng/mL	Med.	252	180
	P25–P75	210–338	147–241
	P	0.04
HMGB-1 (admission); ng/mL	Med.					15.9	8.4
	P25–P75					5.37–30.1	2.6–16
	P					0.047