Research Article
The Influence of Vitamin D Receptor Genetic Variants on Bone Mineral Density and Osteoporosis in Chinese Postmenopausal Women
Table 2
The allelic and genotypic frequencies of VDR genetic variants in the studied subjects.
| | Groups | p.Gly14Ala | p.His305Gln | | Genotypic frequencies (%) | Allelic frequencies (%) | | | Genotypic frequencies (%) | Allelic frequencies (%) | | | | GG | GC | CC | G | C | CC | CG | GG | C | G |
| | Case group ( = 482) | 210 (43.57) | 198 (41.08) | 74 (15.35) | 618 (64.11) | 346 (35.89) | 5.5553 | 0.0622 | 222 (46.06) | 207 (42.94) | 53 (11.00) | 651 (67.53) | 313 (32.47) | 0.2062 | 0.9020 | | Control group ( = 488) | 230 (47.13) | 220 (45.08) | 38 (7.79) | 680 (69.67) | 296 (30.33) | 2.1758 | 0.3369 | 265 (54.30) | 176 (36.07) | 47 (9.63) | 706 (72.34) | 270 (27.66) | 4.7690 | 0.0921 |
| | Total ( = 970) | 440 (45.36) | 418 (43.09) | 112 (11.55) | 1298 (66.91) | 642 (33.09) | 0.7006 | 0.7045 | 487 (50.21) | 383 (39.48) | 100 (10.31) | 1357 (69.95) | 583 (30.05) | 3.5873 | 0.1664 | | | = 13.6018, = 0.0011 | = 6.7816, = 0.0092 | | | = 6.6290, = 0.0364 | = 5.3267, = 0.0210 | | |
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