Research Article
CD73 Predicts Favorable Prognosis in Patients with Nonmuscle-Invasive Urothelial Bladder Cancer
Table 2
Comparison of the immunohistochemical markers with pathologic characteristics (
).
| Variable | Categorization | CD73 expression | Score 0 or 1+ | Score 2+ | |
| Tumor stage (WHO 1973) | pTa | 57 | 33 | 0.006 | pT1 | 57 | 11 | pT2 | 12 | 1 | pT3 | 2 | 0 | pT4 | 0 | 1 | Histologic grade (WHO 1973) | G1 | 31 | 13 | 0.100 | G2 | 60 | 27 | G3 | 37 | 6 | Histologic grade (WHO 2004) | Low grade | 67 | 34 | 0.014 | High grade | 61 | 12 | Adjacent carcinoma in situ | No | 112 | 46 | 0.007 | Yes | 16 | 0 | Multiplicity | Solitary | 87 | 37 | 0.130 | Multifocal | 41 | 9 | Growth pattern | Papillary | 115 | 44 | 0.359 | Solid | 13 | 2 |
| Immunohistochemistry | Ki-67 labelling index | ≤10% | 72 | 36 | 0.008 | >10% | 56 | 10 |
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Chi-square Pearson (2-sided); bold face representing values <0.05. Fisher’s exact test (2-sided); bold face representing values <0.05.
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