Research Article

Aldehyde Dehydrogenase Polymorphisms and Blood Pressure Elevation in the Japanese: A Cross-Sectional and a Longitudinal Study over 20 Years in the Shimane CoHRE Study

Table 4

Association analysis between the BP change and the ALDH2 genotypes.

ALDH2 genotype value
ALDH21/1ALDH21/2 or ALDH22/2

(M/F)339 (119/210)231 (93/138)n/s
SBP11.0 ± 0.212.0 ± 1.1n/s
DBP1.0 ± 0.71.0 ± 0.8n/s

SBP and DBP indicate values of increase in systolic blood pressure or diastolic blood pressure, respectively: change in SBP and DBP after 20 years of the observation period. n/s: not significant.