NRAMP1 and VDR Gene Polymorphisms in Susceptibility to Tuberculosis in Venezuelan Population

Table 3

Genotype and allele frequency distribution of NRAMP-3′UTR in TB patients and healthy controls grouped according to the TST.

3′UTR	TGTGdel/del	TGTG+/del	TGTG+/+	Total
Genotypes
Controls TST+ (number of individuals)	0	12	38	50
% of total	0.00	8.6	27.3	36
% within condition	0.00	24.00	76.00
% within 3'UTR	0.00	29.3	40
TB patients (number of individuals)	3	29	57	89
% of total	2.2	20.9	41	64
% within condition	3.4	32.6	64
% within 3'UTR	100.00	70.7	60
Total	3	41	95	139
% of total	2.2	29.5	68.3	100
(df: 2) = 3.15      Cramer’s
3′UTR	TGTGdel/del	TGTG+/del	TGTG+/+	Total
Genotypes
Controls TST− (number of individuals)	0	1	18	19
% of total	0.00	0.9	16.7	17.6
% within condition	0.00	5.3	94.7
% within 3'UTR	0.00	3.3	24
TB patients (number of individuals)	3	29	57	89
% of total	2.8	26.9	52.8	82.4
% within condition	3.4	32.6	64
% within 3'UTR	100.00	96.7	76
Total	3	30	75	108
% of total	2.8	27.8	69.4	100
(df: 2) = 6.97      Cramer’s
3′UTR	TGTGdel/del	TGTG+/del	TGTG+/+	Total
Genotypes
Controls TST− (number of individuals)	0	1	18	19
% of total	0.00	1.4	26.1	27.5
% within condition	0.00	5.3	94.7
% within 3'UTR	0.00	7.7	32.1
Controls TST+ (number of individuals)	0	12	38	50
% of total	0.00	17.4	55.1	72.5
% within condition	0.00	24.00	76.00
% within 3'UTR	0.00	92.3	67.9
Total	0	13	56	69
% of total	0	18.8	81.2	100
(df: 2) = 3.16      Cramer’s

Note. : probability values; df: degree freedom; Cramer’s : measure of association between two variables.