Clinical Study
High-Dose versus Low-Dose Vitamin D Supplementation and Arterial Stiffness among Individuals with Prehypertension and Vitamin D Deficiency
Table 1
Mean baseline characteristics (±SEM) of participants randomized to high-dose versus low-dose vitamin D (
= 41).
| | Variable | Low-dose
( = 22) | High-dose
( = 19) |
| | Age (years) | 34.8 ± 12.8 | 40.4 ± 7.5 | | Male (%) | 48 | 52 | | Body Mass Index (kg/m2) | 30.5 ± 5.8 | 32.1 ± 8.7 | | Serum 25-hydroxyvitamin D (ng/mL) | 16.5 ± 6.8 | 15.1 ± 5.7 | | Clinic SBP (mmHg) | 127.8 ± 5.1 | 123.7 ± 4.6 | | Clinic DPB (mmHg) | 78.6 ± 1.9 | 76.9 ± 3.1 | | Clinic heart rate (bpm) | 79.3 ± 2.5 | 76.7 ± 3.1 | | 24 hr mean ambulatory SBP (mmHg) | 125.8 ± 9.9 | 126.1 ± 9.4 | | 24 hr mean ambulatory DBP (mmHg) | 77.5 ± 8.7 | 78.2 ± 8.0 | | Daytime ambulatory SBP (mmHg) | 128.0 ± 10.4 | 128.3 ± 8.8 | | Daytime ambulatory DBP (mmHg) | 79.6 ± 8.9 | 80.5 ± 7.7 | | Nighttime ambulatory SBP (mmHg) | 114.4 ± 10.9 | 118.5 ± 13.2 | | Nighttime ambulatory DBP (mmHg) | 70.0 ± 10.2 | 70.0 ± 11.0 | | Season of enrollment (%) | | | | Winter | 48 | 47 | | Spring | 23 | 21 | | Summer | 16 | 21 | | Fall | 13 | 11 |
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SBP, systolic blood pressure; DBP, diastolic blood pressure; ; high-dose versus low-dose.
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