Research Article
Genome-Wide Scan for Methylation Profiles in Keloids
Table 1
Breakdown of 685 differentially methylated Tier 3 CpGs1.
| A: methylation status of 685 CpGs | | Hypermethylated | 175 (26%) | Hypomethylated | 510 (74%) | B: 685-CpG distribution in promoter versus nonpromoter | | Promoter | 190 (28%) | Nonpromoter | 495 (72%) | C: methylation status of 190 promoter CpGs | | Hypermethylated | 62 (33%) | Hypomethylated | 128 (67%) | D: 190-CpG distribution in promoter regions | | TSS200 | 29% | TSS1500 | 26% | 5′UTR | 41% | First exon | 4% | E: methylation status of 152 genes associated with the 190 CpGs | | Hypermethylated | 56 (37%) | Hypomethylated | 96 (63%) |
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CpG (cytosine-phosphodiester bond-guanine); TSS (transcription start site); UTR (untranslated region).
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