Disease Markers / 2015 / Article / Tab 2 / Research Article
Hyperoxia-Induced Protein Alterations in Renal Rat Tissue: A Quantitative Proteomic Approach to Identify Hyperoxia-Induced Effects in Cellular Signaling Pathways Table 2 Proteins significantly regulated and identified by MALDI-TOF with characteristic features and induction factors (IF) at day 0 (T0), day 3 (T3), and day 7 (T7).
Spot number Figure Molecular weight [kDa] Significance, Protein Mascot score Protein name Accession number T0 T3 T7 46 Figure 3(d) ~100 0.0026 Not identified
— n.s. n.s. n.s. 50 Figure 3(d) ~100 0.036 Not identified — n.s. n.s. n.s. 239
Figure 3(b) 72 0.012 71 Meprin A subunit alpha MEP1A_RAT n.s. −4.17 n.s. 322 Figure 3(c) 70 0.022 23 Microtubule-associated tumor suppressor 1 homolog MTUS1_RAT n.s. 8.12 8.12 759 Figure 3(d) 33 0.035 90 40S ribosomal protein SA RSSA_RAT −1.77 −1.77 −1.77 841 Figure 3(b) 30 0.012 Not identified — n.s. n.s. n.s. 921 Figure 3(b) 29 0.011 202 Fructose-1,6-bisphosphatase 1 F16P1_RAT n.s. −1.87 n.s. Stomatin-like protein 2, mitochondrial STML2_RAT 3′(2′),5′-bisphosphate nucleotidase 1 BPNT1_RAT Legumain LGMN_RAT
924
Figure 3(d)
28
0.03
64 ATP synthase subunit alpha mitochondrial ATPA_RAT n.s. −1.81 −1.81 Voltage-dependent anion selective channel protein 1 VDAC1_RAT 957 Figure 3(b) 28 0.042 256 Fructose-1,6-bisphosphatase 1 F16P1_RAT n.s. n.s. 1.74 Actin, cytoplasmic 2 ACTG_RAT Actin, cytoplasmic 1 ACTB_RAT 1402 Figure 3(a) 23 0.018 60 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform 2ABA_RAT 1.74 1.74 1.74 1405 Figure 3(a) 23 0.012 60 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform 2ABA_RAT 1.74 1.74 1.74 1928 Figure 3(a) 14 0.033 59 Ras-related protein Rab-1A RAB1A_RAT 1.81 n.s. n.s. 1957 Figure 3(d) 14 0.0028 Not identified — n.s. n.s. n.s. 2048 Figure 3(d) 13 0.0096 Not identified — n.s. n.s. n.s.
