Clinical Study

Prognostic Value of Neutrophil-Related Factors in Locally Advanced Cervical Squamous Cell Carcinoma Patients Treated with Cisplatin-Based Concurrent Chemoradiotherapy

Table 4

Association between RNG and clinicopathologic characteristics of LACSCC patients with neutropenia.

Clinicopathologic characteristicsRNG, (%) value
≥3.01<3.01

Age
 ≤50 years11 (52.4)10 (47.6)0.890
 >50 years7 (50.0)7 (50.0)
Histologic grade
 Well and moderately differentiated7 (50.0)7 (50.0)0.890
 Poorly differentiated11 (52.4)10 (47.6)
Tumor size
 ≤4 cm5 (55.6)4 (44.4)0.921
 >4 cm13 (50.0)13 (50.0)
Parametrial invasion
 No6 (42.9)8 (57.1)0.462
 Unilateral9 (64.3)5 (35.7)
 Bilateral3 (42.9)4 (57.1)
Clinical lymph node involvement
 cN07 (33.3)14 (66.7)0.023
 cN111 (78.6)3 (21.4)
FIGO stage
 II9 (52.9)8 (47.1)0.862
 III9 (50.0)9 (50.0)
Hemoglobin levels at diagnosis (g/dL)
 ≤1134 (44.4)5 (55.6)0.921
 >11314 (53.8)12 (46.2)
Platelets at diagnosis (g/dL)
 ≤3203 (75.0)1 (25.0)0.638
 >32015 (48.3)16 (51.7)
Response
 CR7 (36.8)12 (63.2)0.060
 Non-CR11 (68.8)5 (31.2)

RNG, responses of neutrophil to granulocyte colony-stimulating factors; LACSCC, locally advanced cervical squamous cell carcinomas; FIGO, International Federation of Gynecology and Obstetrics; CR, complete response.