Research Article

Contribution of BRCA1 and BRCA2 Germline Mutations to Early Algerian Breast Cancer

Table 1

Clinical characteristics of study population: age at diagnosis, at menarche, at first pregnancy, and at first use of oral contraceptive.

Mean age (years)BRCA mutation carriersNoncarriers
BRCA1BRCABRCA2

At diagnosis37.75 34.63 31.50 37.06

At menarche15.00
≤12: 00%
13-14: 25%
15-16: 75%
13.63
≤12: 14.2%
13-14: 21.3%
15-16: 21.4%
12.25
≤12: 50%
13-14: 50%
15-16: 00%
14.13
≤12: 15.7%
13-14: 40.6%
15-16: 40.7%
>16: 03.1%

At first pregnancy22.25 24.0026.33 26.50

At first use of oral contraceptive 26.00 26.29 26.66 26.15