Research Article
Immunohistochemical Expression of VEGF and Podoplanin in Uterine Cervical Squamous Intraepithelial Lesions
Table 3
Correlation between VEGF and PDPN immunoexpression in squamous intraepithelial lesions.
| Diagnosis | VEGF | PDPN |
Total | value |
Negative or focal | Diffuse | | % | | % | | % |
| Control | Negative or weak | 7 | 77.8 | 19 | 55.9 | 26 | 60.5 | 0.147 | Moderate | 1 | 11.1 | 14 | 41.2 | 15 | 34.9 | Strong | 1 | 11.1 | 1 | 2.9 | 2 | 4.7 | Total | 9 | 100 | 34 | 100 | 43 | 100 |
| CIN 1 | Negative or weak | 4 | 44.4 | 30 | 68.2 | 34 | 64.2 | 0.252 | Moderate | 3 | 33.3 | 6 | 13.6 | 9 | 17.0 | Strong | 2 | 22.2 | 8 | 18.2 | 10 | 18.9 | Total | 9 | 100 | 44 | 100 | 53 | 100 |
| CIN 2 | Negative or weak | 2 | 16.7 | 22 | 45.8 | 24 | 40.0 | 0.110 | Moderate | 7 | 58.3 | 14 | 29.2 | 21 | 35.0 | Strong | 3 | 25.0 | 12 | 25.0 | 15 | 25.0 | Total | 12 | 100 | 48 | 100 | 60 | 100 |
| CIN 3 | Negative or weak | 4 | 13.3 | 21 | 43.8 | 25 | 32.1 | 0.018 | Moderate | 8 | 26.7 | 7 | 14.6 | 15 | 19.2 | Strong | 18 | 60.0 | 20 | 41.7 | 38 | 48.7 | Total | 30 | 100 | 48 | 100 | 78 | 100 |
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Fisher’s exact test; Chi-square test.
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