HER2 Protein Overexpression and Gene Amplification in Plasmacytoid Urothelial Carcinoma of the Urinary Bladder

Table 2

HER2 IHC and FISH results.

Case	Component	HER2 IHC	HER2 gene; amplification	HER2/CEP17  ratio	Average HER2; copy number
1	P	Positive (3+)	Positive	5.8	20.0
	CONV	Positive (3+)	Positive	3.03	9.0
2	P	Positive (3+)	Positive	3.61	9.8
	MP	Positive (3+)	Positive	2.2	9.0
	CONV	Positive (3+)	Positive	2.13	7.5
3	P	Negative (0)	Positive	2.06	4.9
	CONV	Negative (0)	Negative	1.27	2.0
4	P	Equivocal (2+)	Equivocal	1.81	4.9
5	P	Positive (3+)	Negative	1.68	3.5
6	P	Positive (3+)	Equivocal	1.61	4.5
	CONV	Positive (3+)	Negative	1.07	3.2

P, plasmacytoid component; CONV, conventional component; MP, micropapillary component.