Functional Analysis of the Coronary Heart Disease Risk Locus on Chromosome 21q22

Figure 4

Expression of (a) SLC5A3 and (b) MRPS6 in aortic intima media presented by rs9982601 genotype in the ASAP study. The minor allele of rs9982601 was associated with higher expression of both SLC5A3 (1.30-fold (95% CIs 1.16–1.47) per A allele = 3.98 × 10⁻⁵) and MRPS6 (1.15-fold (95% CIs 1.06–1.25) per A allele = 9.60 × 10⁻⁴).

(a)

(b)