Research Article

Combined Genetic Biomarkers Confer Susceptibility to Risk of Urothelial Bladder Carcinoma in a Saudi Population

Table 4

Effect of SNP allele percentages on phenotypes of 42 smokers with UBC.

SNP IDWild-type allele
(%)
Variant allele (%) ( value)

GSTM1 (+,−)40 (47.6)44 (52.4)0.4 (0.5)
GSTT1 (+,−)72 (85.7)12 (14.3)85.1 (<0.0001)
rs4646903 T>C70 (83.3)14 (16.7)74.1 (<0.0001)
rs1048943 A>G78 (92.9)6 (7.1)122.9 (<0.0001)
rs1042522 Pro>Arg40 (47.5)44 (52.5)0.4 (0.5)
rs1801133 C>T74 (88.1)10 (11.9)97.0 (<0.0001)
rs1801394 A>G30 (35.7)54 (64.3)13.7 (0.0002)