Research Article
Combined Genetic Biomarkers Confer Susceptibility to Risk of Urothelial Bladder Carcinoma in a Saudi Population
Table 4
Effect of SNP allele percentages on phenotypes of 42 smokers with UBC.
| SNP ID | Wild-type allele (%) | Variant allele (%) | ( value) |
| GSTM1 (+,−) | 40 (47.6) | 44 (52.4) | 0.4 (0.5) | GSTT1 (+,−) | 72 (85.7) | 12 (14.3) | 85.1 (<0.0001) | rs4646903 T>C | 70 (83.3) | 14 (16.7) | 74.1 (<0.0001) | rs1048943 A>G | 78 (92.9) | 6 (7.1) | 122.9 (<0.0001) | rs1042522 Pro>Arg | 40 (47.5) | 44 (52.5) | 0.4 (0.5) | rs1801133 C>T | 74 (88.1) | 10 (11.9) | 97.0 (<0.0001) | rs1801394 A>G | 30 (35.7) | 54 (64.3) | 13.7 (0.0002) |
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