A Novel Panel of Serum Biomarkers for MPM Diagnosis

Table 2

Biomarkers data were reported as mean ± SD (standard deviation) or median and 25°–75° percentile. The value was considered significant when it was <0.5 ().

Marker	Unit	Subjects	Mean ± SD	Min	Max	value
Eotaxin	pg/mL	Workers; MPM	168.48 ± 74.02; 165.70 ± 67.04	36.00; 63.40	337.19; 322.27	0.875
VEGF	pg/mL	Workers; MPM	2133.19 ± 6066.87; 459.25 ± 541.43	20.60; 108.8	30140.00; 3013.60	0.79
HGF	pg/mL	Workers; MPM	337.49 ± 142.40; 634.56 ± 436.26	155.83; 83.25	832.56; 1972.15
Lamin	ng/mL	Workers; MPM	4875.15 ± 1723.54; 4446.35 ± 1049.46	622.27; 2642.23	9856.80; 7305.91	0.287
Vimentin	ng/mL	Workers; MPM	6.26 ± 2.34; 8.06 ± 3.79	1.73; 1.14	13.18; 21.16
			Median	25° percentile	75° percentile
Timp3	pg/mL	Workers; MPM	29.60; 27.20	18.41; 16.87	41.04; 36.43	0.6
THSP2	pg/mL	Workers; MPM	21525; 12370	15175; 8395	26700; 21220
SMRP	nM	Workers; MPM	0.72; 1.35	0.50; 0.94	1.15; 3.07
pOPN	ng/mL	Workers; MPM	225.8; 555.0	167.0; 249.7	302.6; 911.2
IL6	pg/mL	Workers; MPM	11.4; 22.81	7.4; 14.85	14.8; 39.26
TNFa	pg/mL	Workers; MPM	28.58; 32.65	19.33; 22.03	37.91; 42.41	0.655
IL5	pg/mL	Workers; MPM	6.32; 6.91	5.21; 4.33	9.96; 10.97	0.942
FGF basic	pg/mL	Workers; MPM	74.85; 82.71	51.72; 53.90	104.18; 115.11	0.534
PDGF-bb	pg/mL	Workers; MPM	7084.53; 5941.01	4095.57; 2734.14	9098.03; 9309.93	0.591
IP10	pg/mL	Workers; MPM	941.15; 1565.34	791.68; 1122.36	1444.00; 2421.65
CTAK	pg/mL	Workers; MPM	578.34; 566.95	461.75; 450.95	780.41; 896.65	0.947
SCGFb	pg/mL	Workers; MPM	56887; 47188	28627; 37715	77644; 61507	0.686
Desmin	ng/mL	Workers; MPM	48.79; 66.05	42.98; 47.37	58.78; 292.76
Fibulin	ng/mL	Workers; MPM	372.94; 385.55	251.31; 155.87	430.12; 533.33	0.983