The Immunosignature of Mother/Fetus Couples in Gestational Diabetes Mellitus: Role of HLA-G 14 bp ins/del and PAPP-A A/C Polymorphisms in the Uterine Inflammatory Milieu

Table 1

Major clinical characteristics of gestational diabetes mellitus (GDM) mothers and healthy mothers (controls). Continuous variables are expressed as mean (sd), categorical variables as n (%).

Clinical data	GDM	Controls	value
Age	35.3 (5.4)	34.3 (4.6)	0.35
First trimester week maternal body mass index	24.8 (4.8)	22.6 (3.6)	0.01
Maternal weight at first trimester of gestation (kg)	66.0 (14.0)	61.3 (11.0)	0.05
Maternal weight at delivery (kg)	74.6 (14.5)	72.9 (11.4)	0.52
Maternal BMI ≥ 25	12 (46%)	31 (21%)	0.005
Week of gestation at delivery	38.2 (2.5)	39.1 (1.5)	0.01
Birth weight (g)	3261 (562)	3243 (461)	0.86
Birth weight > 90 centile	6 (27%)	11 (8%)	0.01
Cesarean section	10 (38%)	57 (38%)	0.96
Newborn gender (males)	10 (38%)	83 (55%)	0.15
First gestation	13 (50%)	66 (44%)	0.35
Induction	9 (35%)	40 (26%)	0.48
Familiarity for diabetes	14 (54%)	39 (26%)	0.009