Serum HMGB1 as a Potential Biomarker for Patients with Asbestos-Related Diseases

Table 4

Relationship between HMGB1 and MMPs covariates in study groups.

Group	Coefficient	(HMGB1, MMP2)	(HMGB1, MMP9)	(MMP2, MMP9)
Healthy		0.1998	0.2580	0.586
		0.0949	0.0298	<0.001
AE < 10 Y		0.2215	0.2721	0.345
		0.0037	0.0003	<0.001
AE ≥ 10 Y		0.2345	0.1456	0.269
		0.0075	0.0997	0.002
PP		0.0677	0.0099	0.494
		0.5483	0.9303	<0.001
Asbestosis		−0.0343	−0.1347	0.018
		0.8548	0.4701	0.925
MPM		0.0821	0.3464	0.725
		0.7710	0.2059	0.002

AE: asbestos-exposed; PP: pleural plaques; Y: years; : Spearman’s rank correlation coefficient.