Association of Single-Nucleotide Polymorphisms in DC-SIGN with Nasopharyngeal Carcinoma Susceptibility

Table 2

Frequencies of genotypes at DC-SIGN rs7252229 in NPC patients and healthy controls.

Genotype	Cases	Controls	Unadjusted OR (95%CI)	P	Adjusted OR (95%CI)	Adjusted P	PHWE
rs7252229							0.307
CC	8	1	1.000		1.000
GC	65	73	0.111 (0.014–0.914)	0.041	0.076 (0.008–0.690)	0.022
GG	404	486	0.104 (0.013–0.834)	0.033	0.056 (0.006–0.487)	0.009
GC + GG	469	559	0.105 (0.013–0.842)	0.034	0.059 (0.007–0.515)	0.010

Calculated using multiple logistic regression after controlling for age, sex, smoking history, and EBV infection factors. CI: confidence interval; DC-SIGN: dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin; HWE: Hardy-Weinberg equilibrium; NPC: nasopharyngeal carcinoma; OR: odds ratio.