Association of Single-Nucleotide Polymorphisms in DC-SIGN with Nasopharyngeal Carcinoma Susceptibility

Table 3

Frequencies of genotypes at DC-SIGN rs2287886 in NPC patients and healthy controls.

Genotype	Cases	Controls	Unadjusted OR (95%CI)	P	Adjusted OR; (95%CI)	Adjusted P	PHWE
rs2287886							0.331
AA	236	294	1.000		1.000
AG	202	229	1.099 (0.851–1.418)	0.469	1.174 (0.778–1.772)	0.444
GG	38	36	1.315 (0.808–2.140)	0.270	0.819 (0.345–1.94)	0.651

Calculated using multiple logistic regression after controlling for age, sex, smoking history, and EBV infection factors. CI: confidence interval; DC-SIGN: dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin; HWE: Hardy-Weinberg equilibrium; NPC: nasopharyngeal carcinoma; OR: odds ratio.