Association of Single-Nucleotide Polymorphisms in DC-SIGN with Nasopharyngeal Carcinoma Susceptibility

Table 4

Frequencies of genotypes at DC-SIGN rs4804803 in NPC patients and healthy controls.

Genotype	Cases	Controls	Unadjusted OR (95%CI)	P	Adjusted OR; (95%CI)	Adjusted P	PHWE
rs4804803							0.533
AA	400	480	1.000		1.000
AG	69	78	1.062 (0.748–1.506)	0.738	1.269 (0.803–2.005)	0.307
GG	8	2	4.800 (1.014–22.732)	0.048	9.038 (1.708–47.822)	0.010
GG + AG	77	80	1.155 (0.822–1.623)	0.406	1.447 (0.934–2.241)	0.098

Calculated using multiple logistic regression after controlling for age, sex, smoking history, and EBV-VCA-IgA status. CI: confidence interval; DC-SIGN: dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin; HWE: Hardy-Weinberg equilibrium; NPC: nasopharyngeal carcinoma; OR: odds ratio.