Research Article
The Expression and Related Clinical Significance of SIRT3 in Non-Small-Cell Lung Cancer
Table 3
Univariate analysis of the correlation between clinical indicators/SIRT3 expression and prognosis.
| Clinical indicator | N | 5-year survival rate (%) | Chi-square | Log-rank test () |
| SIRT3 expression level | | | | | Low | 54 | 87.0 | 20.525 | 0.000 | Medium | 66 | 56.1 | High | 11 | 27.3 | Sex | | | | | Male | 73 | 64.4 | 0.800 | 0.371 | Female | 58 | 69.0 | Age | | | | | ≥60 | 80 | 65.0 | 0.515 | 0.473 | <60 | 51 | 68.6 | Pathological type | | | | | SCC | 39 | 56.4 | 2.791 | 0.095 | ACA | 92 | 70.7 | Tumor size | | | | | ≤2 | 49 | 83.7 | 10.972 | 0.004 | 2-3 | 41 | 60.5 | ≥3 | 41 | 51.3 | Tumor site | | | | | Left lung | 52 | 67.1 | 0.364 | 0.546 | Right lung | 79 | 65.4 | Lymphatic metastasis | | | | | Yes | 39 | 41.0 | 28.188 | 0.000 | No | 92 | 77.2 | Pleural invasion | | | | | Yes | 41 | 70.7 | 0.202 | 0.653 | No | 90 | 64.4 | Degree of differentiation | | | | | Low | 36 | 50.0 | 10.952 | 0.004 | Medium | 62 | 72.6 | High | 33 | 72.7 | Clinical stage | | | | | 0 | 11 | 100 | 16.092 | 0.001 | I | 45 | 75.6 | II | 53 | 62.3 | III | 22 | 40.9 |
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