Detection of Pathological Changes in the Aorta during Thoracic Aortic Aneurysm Progression on Molecular Level

Figure 1

Expression of marker genes on mRNA levels in tissue of the patients with different stages of TAA. The mRNA levels of all detected genes were compared to controls (C, ). All data are presented as average ± SD: 1—mean aortic diameter 43 ± 2.3 mm (), 2—mean aortic diameter 51 ± 2.8 mm (), and 3—mean aortic diameter 59.5 ± 3.7 (). , , and mean statistical significance. Maximal levels reached values about 400% higher than controls ().