Detection of Pathological Changes in the Aorta during Thoracic Aortic Aneurysm Progression on Molecular Level

Table 1

Demographic and clinical characteristics of subjects.

	Control	Stage 1	Stage 2	Stage 3
Number of patients	35	12	34	14
Gender (female %)	20/35 (57%)	2/12 (17%)	5/34 (14.7%)	2/14 (14.3%)
Age (years)	45 ± 9.6	49.9 ± 16.6	55.1 ± 14.7	54.5 ± 14.1
Aorta diameter (mm)	—	43 ± 2.3	51 ± 2.8	59.5 ± 3.7
AR/AS	—	6/6 (50/50%)	19/15 (56/44%)	8/6 (57/4%)
BAV/TAV	—	8/4 (67%)	21/13 (62%)	8/6 (57%)
Hypertension	5/35 (14%)	8/12 (67%)	18/34 (52.9%)	12/14 (85.7%)
Diabetes mellitus	0	1/12 (8%)	3/34 (8.8%)	2/14 (14.3%)
Current smokers	9/35 (26%)	7/12 (58.3%)	22/34 (64.7%)	11/14 (78.6%)
BMI	26.4 ± 4.2	29.4 ± 6.4	29.6 ± 4.9	26.99 ± 4.9
Weight (kg)	76.9 ± 15.2	89.2 ± 16.9	89.3 ± 13.7	87.4 ± 16.3