Measurement of Serum Klotho in Systemic Sclerosis

Table 1

Demographic and clinical characteristics of SSc patients.

Characteristics	Scleroderma patients (number 81)
Age (years) (mean ± standard deviation)	63.9 ± 13.1
Sex (F/M) (number)	74/7
Disease duration (years) (mean ± standard deviation)	12.4 ± 8.9
Clinical form (limited/diffuse) (number)	59/22
Antinucleus autoantibody positivity (number)	74
Anticentromere autoantibody positivity (number)	41
Anti-SCL70 autoantibody positivity (number)	19
Erythrocyte sedimentation ratio, 1st hour mm (median, range)	15, 2.0–84
C-reactive protein, mg/L (median, range)	2.1, 0–24
Serum creatinine, mg/dL (median, range)	0.7, 0.49–2.22
Digital ulcers (number)	18
Calcinosis (number)	14
Pulmonary artery hypertension screened through 2D echocardiography (number)	19
Lung interstitial disease (number)	35
Diffusing capacity or transfer factor of the lung for carbon monoxide per unit alveolar volume (%) (mean ± standard deviation)	83.3 ± 15.2
		Vital capacity (%) (mean ± standard deviation)	100.3 ± 17.4
Medsger’s scale score (mean ± standard deviation)	4.3 ± 2.3
Modified Rodnan skin score (median, range)	4.5, 0–30
Osteoporosis (number)	32