Differential Associations for Salivary Sodium, Potassium, Calcium, and Phosphate Levels with Carotid Intima Media Thickness, Heart Rate, and Arterial Stiffness
Table 3
Associations for salivary calcium and phosphate with age, sex, and cardiometabolic phenotypes.
Dependent
Calcium
Phosphate
Regr coeff ± SE
R2
Prob level
Regr coeff ± SE
R2
Prob level
Univariate
Age (years)
0.0044 ± 0.00112
5.1%
0.0005
0.10 ± 0.02
8.5%
<0.0001
Women (yes)
0.0073 ± 0.0279
0.0%
0.79
−0.17 ± 0.51
0.0%
0.73
PP (mmHg)
0.0020 ± 0.0008
2.6%
0.01
0.037 ± 0.014
2.9%
0.01
HR (min−1)
0.0035 ± 0.0012
3.5%
0.004
0.052 ± 0.022
2.2%
0.02
cIMT (mm)
0.33 ± 0.11
3.9%
0.003
7.38 ± 2.01
5.6%
0.0003
Carotid plaque (yes)
0.068 ± 0.026
3.0%
0.01
1.15 ± 0.45
2.8%
0.01
cfPWV (m/s)
0.0097 ± 0.0036
3.1%
0.008
0.24 ± 0.06
6.7%
0.0001
Hypertesion (yes)
0.050 ± 0.026
1.6%
0.054
0.90 ± 0.47
1.6%
0.054
CV disease (yes)
0.044 ± 0.042
0.5%
0.29
0.72 ± 0.72
0.4%
0.32
Diabetes (yes)
0.27 ± 0.11
2.5%
0.02
−1.46 ± 1.78
0.3%
0.41
Metabolic syndrome (yes)
0.054 ± 0.026
1.9%
0.04
0.84 ± 0.46
1.5%
0.07
BMI (kg/m2)
0.0051 ± 0.0033
1.0%
0.12
0.082 ± 0.063
0.7%
0.19
Age adjusted
Women
−0.007 ± 0.028
0.0%
0.80
−0.49 ± 0.49
0.4%
0.32
PP (mmHg)
0.0001 ± 0.00001
0.2%
0.48
0.0002 ± 0.016
0.0%
0.86
HR (min−1)
0.0033 ± 0.0011
3.0%
0.007
0.047 ± 0.022
1.9%
0.04
cIMT (mm)
0.15 ± 0.13
0.5%
0.27
3.22 ± 2.41
0.7%
0.18
Carotid plaque (yes)
0.033 ± 0.028
0.6%
0.24
0.37 ± 0.48
0.2%
0.45
cfPWV (m/s)
0.0042 ± 0.0042
0.4%
0.33
0.14 ± 0.07
1.6%
0.047
Hypertesion (yes)
0.017 ± 0.027
0.2%
0.54
0.05 ± 0.50
0.0%
0.92
CV disease (yes)
0.027 ± 0.041
0.2%
0.51
0.33 ± 0.70
0.1%
0.63
Diabetes (yes)
0.26 ± 0.11
2.2%
0.02
−2.11 ± 1.70
0.6%
0.22
Metabolic syndrome (yes)
0.034 ± 0.026
0.7%
0.19
0.32 ± 0.46
0.2%
0.48
BMI (kg/m2)
0.0052 ± 0.0032
1.1%
0.11
0.078 ± 0.060
0.7%
0.21
Model 1
Age (years)
0.0042 0.0012
4.6%
0.0009
0.069 ± 0.026
2.7%
0.01
PP (mmHg)
—
—
0.57
—
—
0.91
HR (min−1)
0.0033 0.0012
3.0%
0.007
0.050 ± 0.021
2.2%
0.02
cIMT (mm)
—
—
0.29
4.68 ± 2.37
1.6%
0.049
Carotid plaque (yes)
—
—
0.21
—
—
0.58
cfPWV (m/s)
—
—
0.65
—
—
0.35
Model
8.0%
12.6%
Model 2
Age (years)
0.0041 0.0012
4.3%
0.001
0.069 ± 0.026
2.7%
0.01
PP (mmHg)
—
—
0.58
—
—
0.91
HR (min−1)
0.0034 0.0012
3.3%
0.004
0.050 ± 0.021
2.2%
0.02
cIMT (mm)
—
—
0.34
4.68 ± 2.37
1.6%
0.049
Carotid plaque (yes)
—
—
0.31
—
—
0.58
cfPWV (m/s)
—
—
0.60
—
—
0.35
Hypertesion (yes)
—
—
0.99
—
—
0.69
CV disease (yes)
—
—
0.46
—
—
0.34
Diabetes (yes)
0.27 0.11
2.5%
0.01
—
—
0.25
Metabolic syndrome (yes)
—
—
0.43
—
—
0.42
BMI (kg/m2)
—
—
0.33
—
—
0.28
Model
10.6%
12.6%
Regr coeff: regression coefficient; SE: standard error; prob level: probability level.