CXCR4/CXCL12 Signaling and Protumor Macrophages in Primary Tumors and Sentinel Lymph Nodes Are Involved in Luminal B Breast Cancer Progression

<div>Double immunofluorescent staining for CXCR4 and CD163 in luminal B BC samples. Representative images of double immunofluorescent staining and confocal microscopy on primary tumors of relapsing (a) and nonrelapsing (b) luminal B BC patients showing that CXCR4-expressing cancer cells (green) and CD163-positive TAMs (red) are localized in the same tumor regions of relapsing luminal B BC. Scale bars represent 50 <i>μ</i>m.</div>

Disease Markers

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Figure 3: CXCR4/CXCL12 Signaling and Protumor Macrophages in Primary Tumors and Sentinel Lymph Nodes Are Involved in Luminal B Breast Cancer Progression 

Figure 3 | CXCR4/CXCL12 Signaling and Protumor Macrophages in Primary Tumors and Sentinel Lymph Nodes Are Involved in Luminal B Breast Cancer Progression 