Research Article

MEGF10, a Glioma Survival-Associated Molecular Signature, Predicts IDH Mutation Status

Figure 4

MEGF10 associated genes and their potential functions. (a) Gene set variation analysis of biofunction (migration, proliferation, and apoptosis) and signaling pathway (Hedgehog signaling and MAPK signaling) associated genes in TCGA LGG RNA-seq patients. Gene set enrichment score was analyzed by GSVA package of R. These genes showed higher expression with the MEGF10 expression going from low to high. (b) Above results could be validated in TCGA GBM RNA-seq cohorts.
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