Cell-Free Circulating Methylated SEPT9 for Noninvasive Diagnosis and Monitoring of Colorectal Cancer

Table 2

Positive rate of plasma mSEPT9 in each enrolled group using 2/3 algorithm.

Characteristics	N	mSEPT9		value	value
		N	%
CRC	98	60	61.2	<0.001	Ref.
Adenomas	101	8	7.9	0.006	<0.001
Noncolorectal cancer	76	15	19.7	<0.001	<0.001
Gastric cancer	10	7	70.0
Breast cancer	58	8	13.8
Other cancer	8	0	0.0
Inflammation	30	2	6.7	0.125	<0.001
Gastroenteritis	26	2	7.7
Other Inflammation	4	0	0.0
NED	253	4	1.6	Ref.	<0.001

CRC: colorectal cancer; NED: no evidence of diseases; : compared with NED (ref.); : compared with CRC (ref.).