High Circulating Caspase-Cleaved Keratin 18 Fragments (M30) Indicate Short-Term Mortality in Critically Ill Patients

Table 4

Serum M30 performance as a biomarker to predict ICU or overall mortality.

	ICU mortality	Overall mortality
M30 (U/L) optimal cut-off	250.8	250.8
Sensitivity	0.61	0.54
Specificity	0.68	0.70
Positive predictive value	0.41	0.63
Negative predictive value	0.83	0.59
Youden index	0.29	0.21
LHR+	1.92	1.82
LHR−	0.57	0.65
Diagnostic odds ratio	3.34	2.79

LHR: likelihood ratio.